2016 – 2017 Publications | UAMS Graduate School

Biochemistry & Molecular Biology

Chu R, Alford S, Hart K, Kothari A, Mackintosh S, Kovak M, Chambers TC. Mitotic arrest-induced phosphorylation of Mcl-1 revisited using two-dimensional gel electrophoresis and phosphoproteomics: nine phosphorylation sites identified. Oncotarget. 2016;7(48):78958-78970.

Kothari A, Chambers T. CDK1/2 toolbox in need of an upgrade. Cell Cycle. 2016;15(13):1663-4.

Kothari A, Hittelman W, Chambers T. Cell Cycle-Dependent Mechanisms Underlie Vincristine-Induced Death of Primary Acute Lymphoblastic Leukemia Cells. Cancer Res. 2016;76(12):3553-61.

Cellular Physiology & Molecular Biophysics

Bailey Blackburn J, Pokrovskaya I, Fisher P, Ungar D, Lupashin V. COG Complex Complexities: Detailed Characterization of a Complete Set of HEK293T Cells Lacking Individual COG Subunits. Front Cell Dev Biol. 2016;4:23.

Blackburn J, Lupashin V. Creating Knockouts of Conserved Oligomeric Golgi Complex Subunits Using CRISPR-Mediated Gene Editing Paired with a Selection Strategy Based on Glycosylation Defects Associated with Impaired COG Complex Function. Methods Mol Biol. 2016;1496:145-61.

Comstra H, McArthy J, Rudin-Rush S, Hartwig C, Gokhale A, Zlatic S, Blackburn J, Werner E, Petris M, D’Souza P, Panuwet P, Barr D, Lupashin V, Vrailas-Mortimar A, Faundez V. The interactome of the copper transporter ATP7A belongs to a network of neurodevelopmental and neurodegeneration factors. Elife. 2017;e24722.

Heard M, Melnyk S, Simmen F, Yang Y, Pabona J, Simmen R. High-Fat Diet Promotion of Endometriosis in an Immunocompetent Mouse Model is Associated With Altered Peripheral and Ectopic Lesion Redox and Inflammatory Status.. Endocrinology. 2016;157(7):2870-82.

Simmen F, Heard M, Pabona JMP, Fernandes L, Mercado CP, Simmen RCM. Maternal Metabolic State and Cancer Risk: An Evolving Manifestation of Generational Impact. Parental Obesity: Intergenerational Programming and Consequences. 2016:289-305.

Willett R, Blackburn J, Climer L, Pokrovskaya I, Kudlyk T, Wang W, Lupashin V.COG lobe B sub-complex engages v-SNARE GS15 and functions via regulated interaction with lobe A sub-complex.. Sci Rep. 2016;6:29139.

Bioinformatics

Judkins J, Utecht J, Brochausen M. Easy Extraction of Terms and Definitions with OWL2TL. CEUR Workshop Proc. 2016.

Utecht J, Judkins J, Colvin TJ, Rogers N, Rose R, Alvi M, et al. OOSTT: a Resource for Analyzing the Organizational Structures of Trauma Centers and Trauma Systems. CEUR Workshop Proc. 2016.

Clinical Nutrition

Bell A, Kourourian S, Zeng H, Phelps J, Hakkak R. A Diet Containing a High – Versus Low- Daidzein Level Does Not Protect Against Liver Steatosis in the Obese Female Zucker Rat model. Food & Function. 2017;8:129301298.

Jousheghany F, Phelps J, Crook T, Hakkak R. Relationship between level of HbA1C and breast cancer. BBA Clin. 2016;6:45-48.

Communication Sciences and Disorders

Alanazi A, Nicholson N, Atcherson S, Franklin C, Anders M, Nagaraj N, Franklin J, Highley P. Use of Baby Isao simulator and standardized parents in hearing screening and parent counseling education. American Journal of Audiology. 2016;25:211-223.

Alanazi A, Nicholson N, Atcherson SR, Martin P. The HEARLab cortical tone evaluation (CTE) protocol: A clinical feasibility Study. Journal of Hearing Science. 2016;6(3):54-62.

Nicholson N, Martin P, Smith A, Thomas S, Alanazi A. Home visiting programs for families of children who are deaf or hard of hearing: A systematic review. Journal of Early Hearing Detection and Intervention. 2016;1(2):23-28.

Pharmaceutical Sciences

Groves T, Farris R, Anderson J, Alexander T, Kiffer F, Carter G, Wang J, Boerma M, Allen A. 5-Fluorouracil chemotherapy upregulates cytokines and alters hippocampal dendritic complexity in aged mice. Behav Brain Res. 2017;316:215-224.

Liu X, Gujarathi S, Zhang X, Shao L, Boerma M, Crooks PA, Hauer-Jensen M, Zhou D, Zheng G. Synthesis of (2R,8′ S,3′ E)-δ-tocodienol, a tocoflexol family member designed to have a superior pharmacokinetic profile compared to δ-tocotrienol. Tetrahedron. 2016;72:27-28.

Shah A, Hayes C, Martin B. Characteristics of Initial Prescription Episodes and Likelihood of Long-Term Opioid Use – United States, 2006-2015. MMWR Morb Mortal Wkly Rep. 2017;66(10):265-269.

Wang Y, Chang J, Liu X, Zhang X, Zhang S, Zhang X, Zhou D, Zheng G. Discovery of piperlongumine as a potential novel lead for the development of senolytic agents. Aging. 2016 Nov;8(11):2915-2926.

Yadlapalli J, Ford B, Ketkar A, Wan A, Penthala NR, Eoff RL, Prather P, Dobretsov M Crooks P. Pharmacological characterization and antinociceptive effects of the 6-O-sulfate ester derivative of morphine in rats: Role of delta opioid receptors. Pharmacol Res. 2016;113:335-347.

Interdisciplinary Biomedical Sciences

Atwood D, Beenken K, Loughran A, Meeker D, Lantz T, Graham J, Spencer HJ, Smeltzer MS. XerC Contributes to Diverse Forms of Staphylococcus aureus Infection via agr-Dependent and agr-Independent Pathways. Infect Immun. 2016;84(4):1214-25.

Faramawi MF, Delongchamp R, Said Q, Balamurugan A, Hassan A, Aboulenien S, Ismaeil M. High-blood pressure is associated with visit-to-visit blood pressure variability in the US adults. Blood Press. 2017 Feb;26(1):18-23.

Hadden C, Fahmi T, Cooper A, Savenka A, Lupashin V, Roberts D, Maroteaxu L, Haugel-de Mouzon F, Kilic F. Serotonin transporter protects the placental cells against apoptosis in caspase 3-independent pathway. J Cell Physiol. 2017.

Harrington W, Haji M, Galanzha E, Nedosekin D, Nima Z, Watanabe F, Ghosh A, Biris A, Zharov V. Photoswitchable non-fluorescent thermochromic dye-nanoparticle hybrid probes.. Sci Rep. 2016;6:36417.

Li Y, Cooper A, Odibo I, Ahmed A, Murphy P, Koonce R, Dajani N, Lowery C, Roberts D, Maroteaux L, Kilic F. Discrepancy in Insulin Regulation between Gestational Diabetes Mellitus (GDM) Platelets and Placenta. J Biol Chem. 2016;291(18):9657-65.

Li Y, Hadden C, Cooper A, Ahmed A, Wu H, Lupashin V, Mayeux P, Kilic F. Sepsis-induced elevation in plasma serotonin facilitates endothelial hyperpermeability. Sci Rep. 2016;6:22747.

Loughran A, Gaddy D, Beenken K, Meeker D, Morello R, Zhao H, Byrum S, Tackett A, Cassat J, Smeltzer M. Impact of sarA and Phenol-Soluble Modulins on the Pathogenesis of Osteomyelitis in Diverse Clinical Isolates of Staphylococcus aureus. Infect Immun. 2016;84(9):2586-94.

Meeker D, Beenken K, Mills W, Loughran A, Spencer H, Lynn W, Smeltzer M. Evaluation of Antibiotics Active against Methicillin-Resistant Staphylococcus aureus Based on Activity in an Established Biofilm. Antimicrob Agents Chemother. 2016;60(10):5688-94.

Meeker D, Chen J, Smeltzer M. Could targeted, antibiotic-loaded gold nanoconstructs be a new magic bullet to fight infection? Nanomedicine (Lond). 2016;11(18):2379-82.

Meeker D, Jenkins S, Miller E, Beenken K, Loughran A, Powless A, Muldoon T, Galnzha E, Zharov V, Smeltzer M, Chen J. Synergistic Photothermal and Antibiotic Killing of Biofilm-Associated Staphylococcus aureus Using Targeted Antibiotic-Loaded Gold Nanoconstructs. ACS Infect Dis. 2016;2(4):241-250.

Morelle W, Potelle S, Witters P, Wong S, Climer L, Lupashin V, Matthijs G,Gadomski G, Gadomski T, Jaeken J, Cassima D, Morava E, Foulquier F. Galactose supplementation in TMEM165-CDG patients rescues the glycosylation defects. J Clin Endocrinol Metab. 2017.

Nedosekin DA, Fahmi T, Nima ZA, Nolan J, Cai C, Sarimollaoglu M,Dervishi E, Zharov V. Photoacoustic in vitro flow cytometry for nanomaterial research. Photoacoustics. 2017;6:16-25.

Nembhard WN, Tang X, Hu Z, MacLeod S, Stowe Z, Webber D. Maternal and infant genetic variants, maternal periconceptional use of selective serotonin reuptake inhibitors, and risk of congenital heart defects in offspring: population based study. bmj. 2017.

Nolan J, Sarimollaoglu M, Nedosekin D, Jamshidi-Parsian A, Galanzha E, Kore R, Griffin R, Zharov V. In Vivo Flow Cytometry of Circulating Tumor-Associated Exosomes. Anal Cell Pathol (Amst). 2016;2016:1628057.

Potelle S, Dulary E, Climer L, Duvet S, Morelle W, Vicogne D, Lebredonche E, Houdou M, Spriet C, Krzewinski-Recchi M, Peanne R, Klein A, Krzewinski-Recchi, M, Peanne R, Klein A, DE Bettignies G, Morsomme P, Matthijs G, Marquardt T, Lupashin V, Foulquier F. Manganese-induced turnover of TMEM165. Biochem J. 2017.

Ruebel M, Shankar K, Gaddy D, Lindsey F, Badger T, Andres A. Maternal obesity is associated with ovarian inflammation and upregulation of early growth response factor 1. Am J Physiol Endocrinol Metab. 2016;311(1):E269-77.

Ruebel M, Cotter M, Sims C, Moutos D, Badger T, Cleves M, Shankar K, Andres A. Obesity modulates inflammation and lipid metabolism oocyte gene expression: a single cell transcriptome perspective. J Clin Endocrinol Metab. 2017:3524.

Shields B, Mahmoud F, Taylor E, Byrum S, Sengupta D, Koss B, Baldini G, Ransom S, Cline K, Mackintosh S, Edmondson R, Shalin S, Tackett A. Indicators of responsiveness to immune checkpoint inhibitors. Sci Rep. 2017;7(1):807.

Microbiology and Immunology

Atwood D, Beenken K, Loughran A, Meeker D, Lantz T, Graham J, Spencer H, Smeltzer M. XerC Contributes to Diverse Forms of Staphylococcus aureus Infection via agr-Dependent and agr-Independent Pathways. Infect Immun. 2016;84(4):1214-25.

Colonne PM, Winchell CG, Voth DE. Hijacking Host Cell Highways: Manipulation of the Host Actin Cytoskeleton by Obligate Intracellular Bacterial Pathogens. Front Cell Infect Microbiol. 2016;6(107).

Colonne PM, Winchell CG, Graham JG, Onyilagha FI, MacDonald LJ, Doeppler HR, Storz P, Kurten RC, Beare PA, Heinzen RA, Voth DE. Vasodilator-Stimulated Phosphoprotein Activity Is Required for Coxiella burnetii Growth in Human Macrophages. PLoS Pathog. 2016;12(10).

Fujiwara T, Ye S, Castro-Gomes T, Winchell CG, Andrews NW, Voth DE, Varughese KJ, Mackinstosh SF, Feng Y, Pavlos N, Nakamura T, Manolagas SC, Zhao H. PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis. 2016;1(17).

Graham JG, Winchell CG, Kurten RC, Voth DE. Development of an Ex Vivo Tissue Platform To Study the Human Lung Response to Coxiella burnetii. Infect Immun. 2016;84(5):1438-45.

Jennings J, Beenken K, Skinner R, Meeker D, Smeltzer M, Haggard W, Troxel K. Antibiotic-loaded phosphatidylcholine inhibits staphylococcal bone infection. World J Orthop. 2016;7(8):467-74.

Mahapatra S, Gallaher B, Smith SC, Graham JG, Voth DE, Shaw EI. Coxiella burnetii Employs the Dot/Icm Type IV Secretion System to Modulate Host NF-κB/RelA Activation. Front Cell Infect Microbiol. 2016;6.

Naglak E, Morrison S, Morrison R. IFNγ is Required for Optimal Antibody-Mediated Immunity against Genital Chlamydia Infection. Infect Immun. 2016:IAI.00749-16.

Salinas E, Byrum SD, Moreland LE, Mackintosh SG, Tackett AJ, Forrest JC. Identification of viral and host proteins that interact with MHV68 latency-associated nuclear antigen during lytic replication: A role for Hsc70 in viral replication. J Virol. 2016;90(3):1397-413.

Sifford JM, Stahl JA, Salinas E, Forrest JC. Murine gammaherpesvirus-68 LANA and SOX homologs counteract ATM-driven p53 activity during lytic viral replication. J Virol. 2016;90(3):1397-413.

Neurobiology and Developmental Sciences

Cippitelli A, Domi E, Ubaldi M, Douglas J, Li H, Demopulos G, Gaitanaris G, Roberto M, Drew P, Kane C, Ciccocioppo R. Protection against alcohol-induced neuronal and cognitive damage by the PPARγ receptor agonist pioglitazone. Brain Behav Immun. 2017;S0889-1591(17):30023-5.

D’Onofrio S, Urbano F, Messias E, Garcia-Rill E. Lithium decreases the effects of neuronal calcium sensor protein 1 in pedunculopontine neurons. Physiol Rep. 2016;4(6):e12740.

Garcia-Rill E, D’Onofrio S, Mahaffey S. Bottom-up Gamma: the Pedunculopontine Nucleus and Reticular Activating System. Transl. Brain Rhythm. Transl Brain Rhythm. 2016;1:49-53.

Garcia-Rill E, D’Onofrio S, Luster B, Mahaffey S, Urbano F, Phillips C. The 10 Hz Frequency: A Fulcrum For Transitional Brain States. Transl Brain Rhythm. 2016;1(1):7-13.

Garcia-Rill E, Luster B, D’Onofrio S, Mahaffey S, Bisagno V, Urbano F. Implications of gamma band activity in the pedunculopontine nucleus. J Neural Transm. 2016;123(7):655-65.

Groves TR, Allen AR. Src Family Kinase Inhibitors and their Role in the Treatment of Traumatic Brain Injuries. J Trauma Treat. 2016;5:322.

Luster B, Urbano F, Garcia-Rill E. Intracellular mechanisms modulating gamma band activity in the pedunculopontine nucleus (PPN). Physiol Rep. 2016;4(12):e12787.

Urbano F, Luster B, D’Onofrio S, Mahaffey S, Garcia-Rill E. Recording Gamma Band Oscillations in Pedunculopontine Nucleus Neurons.. J Vis Exp. 2016(115).

Nursing Science

Tsai P, Kitch S, Chang J, James A, Dubbert P, Roca J, Powers C. Tai Chi for post-traumatic stress disorder and chronic musculoskeletal pain: A pilot study. Journal of Holistic Nursing. 2017.

Pharmacology

Ford B, Franks L, Radominska-Pandya A, Prather P. Tamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug Development. PLoS One. 2016;11(12):e0167240.

Ford B, Tai S, Fantegrossi W, Prather P. Synthetic Pot: Not Your Grandfather’s Marijuana. Trends Pharmacol Sci. 2017;38(3):257-276.

Franks L, Ford B, Prather P. Selective Estrogen Receptor Modulators: Cannabinoid Receptor Inverse Agonists with Differential CB1 and CB2 Selectivity. Front Pharmacol. 2016;7:503.