Bioinformatics Larrey, E. K., & Pathak, R. (2022, Nov 2). Radiation-Induced Intestinal Normal Tissue Toxicity: Implications for Altered Proteome Profile. Genes (Basel), 13(11). https://doi.org/10.3390/genes13112006 Biomedical Informatics Abram, K. Z., Udaondo, Z., Nookaew, I., Robeson, M. S., & Jun, S.-R. (2022). Genomic Distance-based Rapid Uncovering of Microbial Population Structures (GRUMPS): a reference free genomic data cleaning […]

Bioinformatics Chappell, K., Manna, K., Washam, C. L., Graw, S., Alkam, D., Thompson, M. D., Zafar, M. K., Hazeslip, L., Randolph, C., Gies, A., Bird, J. T., Byrd, A. K., Miah, S., & Byrum, S. D. (2021). Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer. Mol Omics, 17(5), 677-691. https://doi.org/10.1039/d1mo00117e Manna, […]

Bioinformatics Balasubramaniam, M., Mainali, N., Bowroju, S. K., Atluri, P., Penthala, N. R., Ayyadevera, S., Crooks, P. A., & Shmookler Reis, R. J. (2020). Structural modeling of GSK3beta implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs. Sci Rep, 10(1), 18326. https://doi.org/10.1038/s41598-020-75020-w Bowroju, S. K., Mainali, N., Ayyadevara, S., Penthala, N. R., […]

Biochemistry and Molecular Biology Antoszczak, M., Urbaniak, A., Delgado, M., Maj, E., Borgstrom, B., Wietrzyk, J., Huczynski, A., Yuan, Y., Chambers, T., & Strand, D. (2018). Biological activity of doubly modified salinomycin analogs – Evaluation in vitro and ex vivo. Eur J Med Chem., 156, 510-523. Barnette, D., Davis, M., Dang, N., Pidugu, A., Hughes, […]

Biochemistry and Molecular Biology Delgado, M., Kothari, A., Hittelman, W. N., & Chambers T.C. (2017). Preparation of primary acute lymphoblastic leukemia cells in different cell cycle phases by centrifugal elutriation. J. Vis. Exp., 129, e56418. Urbaniak, A., Delgado, M., Antoszczakb, M., Huczyńskib, A., & Chambers, T. C. (2018). Salinomycin derivatives exhibit activity against primary acute […]

Biochemistry & Molecular Biology Chu R, Alford S, Hart K, Kothari A, Mackintosh S, Kovak M, Chambers TC. Mitotic arrest-induced phosphorylation of Mcl-1 revisited using two-dimensional gel electrophoresis and phosphoproteomics: nine phosphorylation sites identified. Oncotarget. 2016;7(48):78958-78970. Kothari A, Chambers T. CDK1/2 toolbox in need of an upgrade. Cell Cycle. 2016;15(13):1663-4. Kothari A, Hittelman W, Chambers […]

Biochemistry & Molecular Biology Eddy S, Maddukuri L, Ketkar A, Zafar MK, Henninger EE, Pursell ZF, et al. Evidence for the kinetic partitioning of polymerase activity on G-quadruplex DNA. Biochemistry. 2015; 54:3218-30. Gao J, Zybailov BL, Byrd AK, Griffin WC, Chib S, Mackintosh SG, et al. Yeast transcription co-activator Sub1 and its human homolog PC4 […]

Biochemistry and Molecular Biology Alford, S., Kothari, A ., Loeff, F., Eichhorn, J., Sakurikar, N.,  Goselink, H., Saylors, R.L.; Jedema, I., Falkenburg, J.H., Chambers, T.C. BH3 inhibitor sensitivity and bcl-2 dependence in primary acute lymphoblastic leukemia cells. Cancer Res. 2015 Feb 3. [Epub ahead of print]. Eichhorn, J., Kothari, A ., & Chambers, T. Cyclin […]

Biochemistry & Molecular Biology Aaratuthodiyil S, Byrd AK, Raney KD. Structure and mechanisms of SF1 DNA helicases. Adv Exp Med Biol. 2013;767:17-46 Ayyadevara S, Bharill P, Dandapat A, Hu CP, Khaidakov M, Mitra S, Shmookler Reis RJ, Mehta JL.  Aspirin inhibits oxidant stress, reduces aging-associated functional declines, and extends lifespan of Caenorhabditis elegans. Antioxid Redox […]

Biochemistry and Molecular Biology Avaritt NL, Owings R, Reynolds M, Larson SK, Byrum S, Hiatt KM, Smoller BR, Tackett AJ, Cheung WL. Misregulation of Rad50 expression in melanoma cells. J Cutan Pathol. 2012 Jul;39(7):680-4. Ayyadevara S, Bharill P, Dandapat A, Hu C, Khaidakov M, Mitra S, Shmookler Reis RJ, Mehta JL. Aspirin inhibits oxidant stress, […]