Dr. Rahman’s laboratory is interested to study the mechanisms of alternative splicing (AS) and nonsense-mediated mRNA decay (NMD) misregulation in cancer, and the means by which faulty AS or/and NMD can be corrected for therapy. My research utilizes biochemistry, molecular biology, genome editing, transcriptomics, proteomics, computational biology, and antisense pharmacology to study RNA metabolism in normal and cancer cells to contribute in developing effective cancer therapies.