2020-2021 Publications | UAMS Graduate School

Bioinformatics

Balasubramaniam, M., Mainali, N., Bowroju, S. K., Atluri, P., Penthala, N. R., Ayyadevera, S., Crooks, P. A., & Shmookler Reis, R. J. (2020). Structural modeling of GSK3beta implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs. Sci Rep, 10(1), 18326. https://doi.org/10.1038/s41598-020-75020-w

Bowroju, S. K., Mainali, N., Ayyadevara, S., Penthala, N. R., Krishnamachari, S., Kakraba, S., Reis, R. J. S., & Crooks, P. A. (2020). Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of Abeta Self-Aggregation and Metal Chelation-Induced Abeta Aggregation. Molecules, 25(16). https://doi.org/10.3390/molecules25163610

Pornputtapong, N., Acheampong, D. A., Patumcharoenpol, P., Jenjaroenpun, P., Wongsurawat, T., Jun, S. R., Yongkiettrakul, S., Chokesajjawatee, N., & Nookaew, I. (2020). KITSUNE: A Tool for Identifying Empirically Optimal K-mer Length for Alignment-Free Phylogenomic Analysis. Front Bioeng Biotechnol, 8, 556413. https://doi.org/10.3389/fbioe.2020.556413

Yongkiettrakul, S., Wongsurawat, T., Jenjaroenpun, P., Acheampong, D. A., Srimanote, P., Maneerat, K., Visessanguan, W., & Nookaew, I. (2021). Genome sequences of antibiotic-resistant Streptococcus suis strains isolated from human patients and diseased and asymptomatic pigs in Thailand. Infect Genet Evol, 87, 104674. https://doi.org/10.1016/j.meegid.2020.104674

Biomedical Informatics

Abouelenein, S., Williams, T., Baldner, J., & Zozus, M. N. (2020). Analysis of Professional Competencies for the Clinical Research Data Management Profession. Stud Health Technol Inform, 270, 1199-1200. https://doi.org/10.3233/SHTI200361

Abram, K., Udaondo, Z., Bleker, C., Wanchai, V., Wassenaar, T. M., Robeson, M. S., 2nd, & Ussery, D. W. (2021). Mash-based analyses of Escherichia coli genomes reveal 14 distinct phylogroups. Commun Biol, 4(1), 117. https://doi.org/10.1038/s42003-020-01626-5

Abram, K., Udaondo, Z., Bleker, C., Wanchai, V., Wassenaar, T. M., Robeson, M. S., & Ussery, D. W. (2020). What can we learn from over 100,000 Escherichia col genomes? bioRxiv, 708131. https://doi.org/10.1101/708131

Abram, K. Z., & Udaondo, Z. (2020). Towards a better metabolic engineering reference: the microbial chassis. Microb Biotechnol, 13(1), 17-18. https://doi.org/10.1111/1751-7915.13363

Ashby, C., Rutherford, M., Bauer, M. A., Peterson, E. A., Wang, Y., Boyle, E. M., Wardell, C. P., & Walker, B. A. (2020). TarPan: an easily adaptable targeted sequencing panel viewer for research and clinical use. BMC Bioinformatics, 21(1), 144. https://doi.org/10.1186/s12859-020-3477-y

Boyle, E. M., Ashby, C., Tytarenko, R. G., Deshpande, S., Wang, H., Wang, Y., Rosenthal, A., Sawyer, J., Tian, E., Flynt, E., Hoering, A., Johnson, S. K., Rutherford, M. W., Wardell, C. P., Bauer, M. A., Dumontet, C., Facon, T., Thanendrarajan, S., Schinke, C. D., Zangari, M., van Rhee, F., Barlogie, B., Cairns, D., Jackson, G., Thakurta, A., Davies, F. E., Morgan, G. J., & Walker, B. A. (2020). BRAF and DIS3 Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma. Clin Cancer Res, 26(10), 2422-2432. https://doi.org/10.1158/1078-0432.CCR-19-1507

Delhey, L., Shoults, C., Johnson, K., Orloff, M., Faramawi, M. F., & Delongchamp, R. (2021). The difference between hypertension determined by self-report versus examination in the adult population of the USA: Continuous NHANES 1999-2016. J Public Health (Oxf), 43(2), 316-324. https://doi.org/10.1093/pubmed/fdz132

Desai, S., Baghal, A., Wongsurawat, T., Jenjaroenpun, P., Powell, T., Al-Shukri, S., Gates, K., Farmer, P., Rutherford, M., Blake, G., Nolan, T., Sexton, K., Bennett, W., Smith, K., Syed, S., & Prior, F. (2020). Chest imaging representing a COVID-19 positive rural U.S. population. Sci Data, 7(1), 414. https://doi.org/10.1038/s41597-020-00741-6

Garza, M. Y., Rutherford, M. W., Adagarla, B., Eisenstein, E., Kumar, K. R., Zimmerman, K. O., Topaloglu, U., & Zozus, M. (2021). Evaluating Site-Level Implementations of the HL7 FHIR Standard to Support eSource Data Exchange in Clinical Research. Stud Health Technol Inform, 281, 397-401. https://doi.org/10.3233/SHTI210188

Garza, M. Y., Rutherford, M., Myneni, S., Fenton, S., Walden, A., Topaloglu, U., Eisenstein, E., Kumar, K. R., Zimmerman, K. O., Rocca, M., Gordon, G. S., Hume, S., Wang, Z., & Zozus, M. (2020). Evaluating the Coverage of the HL7 ((R)) FHIR ((R)) Standard to Support eSource Data Exchange Implementations for use in Multi-Site Clinical Research Studies. AMIA Annu Symp Proc, 2020, 472-481. https://www.ncbi.nlm.nih.gov/pubmed/33936420

Faramawi, M. F., Abouelenein, S., & Johnson, E. (2021). A case-control study of occupational risk factors for pancreatic cancer in poultry plant workers: a random forest approach. J Public Health (Oxf). https://doi.org/10.1093/pubmed/fdab008

Faramawi, M. F., Delhey, L., Abouelenein, S., & Delongchamp, R. (2020). Metabolic syndrome and P-wave duration in the American population. Ann Epidemiol, 46, 5-11. https://doi.org/10.1016/j.annepidem.2020.04.002

Faramawi, M. F., Orloff, M. S., Delongchamp, R., Wang, Y., Feingold, E., Thapa, S., Jin, J., Delhey, L., Abouelenein, S., Zhang, Q., & Singh, K. P. (2020). Biological Pathways of Long-Term Visit-to-Visit Blood Pressure Variability in the American Population: Cardiovascular Health Study and Women’s Health Initiatives. BioMed Research International, 2020, 7. https://doi.org/http://dx.doi.org/10.1155/2020/3841945

Gautam, B., Gyanwali, G., & Ussery, D. W. (2021). Assessment of Bacterial Load in Polyethylene Terephthalate (PET) Bottled Water Marketed in Kathmandu Valley, Nepal. International Journal of Polymer Science, 2021, 6681249. https://doi.org/10.1155/2021/6681249

Jenjaroenpun, P., Wanchai, V., Ono-Moore, K. D., Laudadio, J., James, L. P., Adams, S. H., Prior, F., Nookaew, I., Ussery, D. W., & Wongsurawat, T. (2020). Two SARS-CoV-2 Genome Sequences of Isolates from Rural U.S. Patients Harboring the D614G Mutation, Obtained Using Nanopore Sequencing. Microbiol Resour Announc, 10(1). https://doi.org/10.1128/MRA.01109-20

Jenjaroenpun, P., Wongsurawat, T., Wadley, T. D., Wassenaar, T. M., Liu, J., Dai, Q., Wanchai, V., Akel, N. S., Jamshidi-Parsian, A., Franco, A. T., Boysen, G., Jennings, M. L., Ussery, D. W., He, C., & Nookaew, I. (2021). Decoding the epitranscriptional landscape from native RNA sequences. Nucleic Acids Res, 49(2), e7. https://doi.org/10.1093/nar/gkaa620

Kandel, S., Sripiboon, S., Jenjaroenpun, P., Ussery, D. W., Nookaew, I., Robeson, M. S., 2nd, & Wongsurawat, T. (2020). 16S rRNA Gene Amplicon Profiling of Baby and Adult Captive Elephants in Thailand. Microbiol Resour Announc, 9(24). https://doi.org/10.1128/MRA.00248-20

Syed, M., Al-Shukri, S., Syed, S., Sexton, K., Greer, M. L., Zozus, M., Bhattacharyya, S., & Prior, F. (2021). DeIDNER Corpus: Annotation of Clinical Discharge Summary Notes for Named Entity Recognition Using BRAT Tool. Stud Health Technol Inform, 281, 432-436. https://doi.org/10.3233/SHTI210195

Syed, M., Syed, S., Sexton, K., Greer, M. L., Zozus, M., Bhattacharyya, S., Syed, F., & Prior, F. (2021). Deep Learning Methods to Predict Mortality in COVID-19 Patients: A Rapid Scoping Review. Stud Health Technol Inform, 281, 799-803. https://doi.org/10.3233/SHTI210285

Syed, M., Syed, S., Sexton, K., Syeda, H. B., Garza, M., Zozus, M., Syed, F., Begum, S., Syed, A. U., Sanford, J., & Prior, F. (2021). Application of Machine Learning in Intensive Care Unit (ICU) Settings Using MIMIC Dataset: Systematic Review. Informatics (MDPI), 8(1). https://doi.org/10.3390/informatics8010016

Syed, S., Baghal, A., Prior, F., Zozus, M., Al-Shukri, S., Syeda, H. B., Garza, M., Begum, S., Gates, K., Syed, M., & Sexton, K. W. (2020). Toolkit to Compute Time-Based Elixhauser Comorbidity Indices and Extension to Common Data Models. Healthc Inform Res, 26(3), 193-200. https://doi.org/10.4258/hir.2020.26.3.193

Syed, S., Syed, M., Prior, F., Zozus, M., Syeda, H. B., Greer, M. L., Bhattacharyya, S., & Garg, S. (2021). Machine Learning Approach to Optimize Sedation Use in Endoscopic Procedures. Stud Health Technol Inform, 281, 183-187. https://doi.org/10.3233/SHTI210145

Syed, S., Syed, M., Syeda, H. B., Garza, M., Bennett, W., Bona, J., Begum, S., Baghal, A., Zozus, M., & Prior, F. (2021). API Driven On-Demand Participant ID Pseudonymization in Heterogeneous Multi-Study Research. Healthc Inform Res, 27(1), 39-47. https://doi.org/10.4258/hir.2021.27.1.39

Syed, S., Syed, M., Syeda, H. B., Prior, F., Zozus, M., Penning, M. L., & Orloff, M. (2020). Document Oriented Graphical Analysis and Prediction. Stud Health Technol Inform, 270, 183-187. https://doi.org/10.3233/SHTI200147

Syed, S., Tharian, B., Syeda, H. B., Zozus, M., Greer, M. L., Bhattacharyya, S., Syed, M., & Prior, F. (2021). Consolidated EHR Workflow for Endoscopy Quality Reporting. Stud Health Technol Inform, 281, 427-431. https://doi.org/10.3233/SHTI210194

Syeda, H. B., Syed, M., Sexton, K. W., Syed, S., Begum, S., Syed, F., Prior, F., & Yu, F., Jr. (2021). Role of Machine Learning Techniques to Tackle the COVID-19 Crisis: Systematic Review. JMIR Med Inform, 9(1), e23811. https://doi.org/10.2196/23811

Walden, A., Kemp, A. S., Larson-Prior, L. J., Kim, T., Gan, J., McCoy, H., Payakachat, N., Ward, W., & Eswaran, H. (2020). Establishing a digital health platform in an academic medical center supporting rural communities. J Clin Transl Sci, 4(5), 384-388. https://doi.org/10.1017/cts.2020.11

Wanchai, V., Nookaew, I., & Ussery, D. W. (2020). ProdMX: Rapid query and analysis of protein functional domain based on compressed sparse matrices. Comput Struct Biotechnol J, 18, 3890-3896. https://doi.org/10.1016/j.csbj.2020.10.023

Clinical Nutrition

Arthur, C., Phelps, J., & Hakkak, R. (2021). Examining weight gain: A retrospective study on preterm newborn growth on a diet exclusively of fortified donor breast milk. Int J Funct Nutr, 2(1), 3. https://doi.org/10.3892/ijfn.2021.13

Clinical and Translational Science

Diaz, E. C., Cleves, M. A., DiCarlo, M., Sobik, S. R., Ruebel, M. L., Thakali, K. M., Sims, C. R., Dajani, N. K., Krukowski, R. A., Borsheim, E., Badger, T. M., Shankar, K., & Andres, A. (2020). Parental adiposity differentially associates with newborn body composition. Pediatr Obes, 15(4), e12596. https://doi.org/10.1111/ijpo.12596

Heard-Lipsmeyer, M. E., Diaz, E. C., Sims, C. R., Sobik, S. R., Ruebel, M. L., Thakali, K. M., Krukowski, R. A., Cleves, M., Borsheim, E., Shankar, K., & Andres, A. (2020). Maternal Adiposity is Associated with Fat Mass Accretion in Female but not Male Offspring During the First 2 Years of Life. Obesity (Silver Spring), 28(3), 624-630. https://doi.org/10.1002/oby.22735

Nienaber, T., Maples, H., & Edgar-Zarate, C. (2020). Salmonella Osteomyelitis in an immunocompetent child: A question of penetration. The Journal of the Arkansas Medical Society, 117, 3. https://viewer.joomag.com/med-journal-sept-2020-final/0815784001597156965?page=18

Stahr, S., Chiang, T. C., Bauer, M. A., Runnells, G. A., Rogers, L. J., Vi Do, H., Kadlubar, S. A., & Joseph Su, L. (2021). LowLevel Environmental Heavy Metals are Associated with Obesity Among Postmenopausal Women in a Southern State. Expo Health, 13(2), 269-280. https://doi.org/10.1007/s12403-020-00381-6

Epidemiology

Jin, J., Robeson, H., Fagan, P., & Orloff, M. S. (2020). Association of PARP1-specific polymorphisms and haplotypes with non-small cell lung cancer subtypes. PLoS One, 15(12), e0243509. https://doi.org/10.1371/journal.pone.0243509

Patel, J., Bircan, E., Tang, X., Orloff, M., Hobbs, C. A., Browne, M. L., Botto, L. D., Finnell, R. H., Jenkins, M. M., Olshan, A., Romitti, P. A., Shaw, G. M., Werler, M. M., Li, J., Nembhard, W. N., & National Birth Defects Prevention, S. (2021). Paternal genetic variants and risk of obstructive heart defects: A parent-of-origin approach. PLoS Genet, 17(3), e1009413. https://doi.org/10.1371/journal.pgen.1009413

Rutlen, C., Orloff, M., Bates, J., & Porter, A. (2021). Crop burning and the prevalence of asthma and COPD emergency department treatments in a rural Arkansas county. J Asthma, 58(3), 293-298. https://doi.org/10.1080/02770903.2019.1708096

Shen, T., Bimali, M., Faramawi, M., & Orloff, M. S. (2020). Consumption of Vitamin K and Vitamin A Are Associated With Reduced Risk of Developing Emphysema: NHANES 2007-2016. Front Nutr, 7, 47. https://doi.org/10.3389/fnut.2020.00047

Syed, S., Syed, M., Syeda, H. B., Prior, F., Zozus, M., Penning, M. L., & Orloff, M. (2020). Document Oriented Graphical Analysis and Prediction. Stud Health Technol Inform, 270, 183-187. https://doi.org/10.3233/SHTI200147

GRADUATE PROGRAM IN INTERDISCIPLINARY BIOMEDICAL SCIENCES

Biochemistry and Molecular Biology

Alkam, D., Jenjaroenpun, P., Ramirez, A. M., Beenken, K. E., Spencer, H. J., & Smeltzer, M. S. (2021). The Increased Accumulation of Staphylococcus aureus Virulence Factors Is Maximized in a purR Mutant by the Increased Production of SarA and Decreased Production of Extracellular Proteases. Infect Immun, 89(4). https://doi.org/10.1128/IAI.00718-20

Barnette, D. A., Schleiff, M. A., Datta, A., Flynn, N., Swamidass, S. J., & Miller, G. P. (2021). Meloxicam methyl group determines enzyme specificity for thiazole bioactivation compared to sudoxicam. Toxicol Lett, 338, 10-20. https://doi.org/10.1016/j.toxlet.2020.11.015

Barnette, D. A., Schleiff, M. A., Osborn, L. R., Flynn, N., Matlock, M., Swamidass, S. J., & Miller, G. P. (2020). Dual mechanisms suppress meloxicam bioactivation relative to sudoxicam. Toxicology, 440, 152478. https://doi.org/10.1016/j.tox.2020.152478

Brown, S. L., & Kendrick, S. (2021). The i-Motif as a Molecular Target: More Than a Complementary DNA Secondary Structure. Pharmaceuticals (Basel), 14(2). https://doi.org/10.3390/ph14020096

Edwards, A. D., Marecki, J. C., Byrd, A. K., Gao, J., & Raney, K. D. (2021). G-Quadruplex loops regulate PARP-1 enzymatic activation. Nucleic Acids Res, 49(1), 416-431. https://doi.org/10.1093/nar/gkaa1172

Flynn, N. R., Ward, M. D., Schleiff, M. A., Laurin, C. M. C., Farmer, R., Conway, S. J., Boysen, G., Swamidass, S. J., & Miller, G. P. (2021). Bioactivation of Isoxazole-Containing Bromodomain and Extra-Terminal Domain (BET) Inhibitors. Metabolites, 11(6). https://doi.org/10.3390/metabo11060390

Kelliher, J., Ghosal, G., & Leung, J. W. C. (2021). New answers to the old RIDDLE: RNF168 and the DNA damage response pathway. FEBS J. https://doi.org/10.1111/febs.15857

Kelliher, J. L., West, K. L., Gong, Q., & Leung, J. W. C. (2020). Histone H2A variants alpha1-extension helix directs RNF168-mediated ubiquitination. Nat Commun, 11(1), 2462. https://doi.org/10.1038/s41467-020-16307-4

Ketkar, A., Smith, L., Johnson, C., Richey, A., Berry, M., Hartman, J. H., Maddukuri, L., Reed, M. R., Gunderson, J. E. C., Leung, J. W. C., & Eoff, R. L. (2021). Human Rev1 relies on insert-2 to promote selective binding and accurate replication of stabilized G-quadruplex motifs. Nucleic Acids Res, 49(4), 2065-2084. https://doi.org/10.1093/nar/gkab041

Koss, B., Shields, B. D., Taylor, E. M., Storey, A. J., Byrum, S. D., Gies, A. J., Washam, C. L., Choudhury, S. R., Hyun Ahn, J., Uryu, H., Williams, J. B., Krager, K. J., Chiang, T. C., Mackintosh, S. G., Edmondson, R. D., Aykin-Burns, N., Gajewski, T. F., Wang, G. G., & Tackett, A. J. (2020). Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion. Cancer Res, 80(21), 4707-4719. https://doi.org/10.1158/0008-5472.CAN-20-0524

Marecki, J. C., Belachew, B., Gao, J., & Raney, K. D. (2021). RNA helicases required for viral propagation in humans. Enzymes, 50, 335-367. https://doi.org/10.1016/bs.enz.2021.09.005

Nyamugenda, E., Griffin, H., Russell, S., Cooney, K. A., Kowalczyk, N. S., Islam, I., Phelan, K. D., & Baldini, G. (2020). Selective Survival of Sim1/MC4R Neurons in Diet-Induced Obesity. iScience, 23(5), 101114. https://doi.org/10.1016/j.isci.2020.101114

Pinson, A. O., Pouncey, D. L., Schleiff, M. A., Fantegrossi, W. E., Prather, P. L., Radominska-Pandya, A., Boysen, G., & Miller, G. P. (2020). Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics. Molecules, 25(20). https://doi.org/10.3390/molecules25204820

Reed, M. R., Maddukuri, L., Ketkar, A., Byrum, S. D., Zafar, M. K., Bostian, A. C. L., Tackett, A. J., & Eoff, R. L. (2021). Inhibition of tryptophan 2,3-dioxygenase impairs DNA damage tolerance and repair in glioma cells. NAR Cancer, 3(2), zcab014. https://doi.org/10.1093/narcan/zcab014

Schleiff, M. A., Flynn, N. R., Payakachat, S., Schleiff, B. M., Pinson, A. O., Province, D. W., Swamidass, S. J., Boysen, G., & Miller, G. P. (2021). Significance of Multiple Bioactivation Pathways for Meclofenamate as Revealed through Modeling and Reaction Kinetics. Drug Metab Dispos, 49(2), 133-141. https://doi.org/10.1124/dmd.120.000254

Schleiff, M. A., Payakachat, S., Schleiff, B. M., Swamidass, S. J., Boysen, G., & Miller, G. P. (2021). Impacts of diphenylamine NSAID halogenation on bioactivation risks. Toxicology, 458, 152832. https://doi.org/10.1016/j.tox.2021.152832

Taylor, E. M., Byrum, S. D., Edmondson, J. L., Wardell, C. P., Griffin, B. G., Shalin, S. C., Gokden, M., Makhoul, I., Tackett, A. J., & Rodriguez, A. (2020). Proteogenomic analysis of melanoma brain metastases from distinct anatomical sites identifies pathways of metastatic progression. Acta Neuropathol Commun, 8(1), 157. https://doi.org/10.1186/s40478-020-01029-x

Taylor, E. M., Koss, B., Davis, L. E., & Tackett, A. J. (2020). Histone Modifications as Biomarkers for Immunotherapy. Methods Mol Biol, 2055, 213-228. https://doi.org/10.1007/978-1-4939-9773-2_10

Trentzsch, M., Nyamugenda, E., Miles, T. K., Griffin, H., Russell, S., Koss, B., Cooney, K. A., Phelan, K. D., Tackett, A. J., Iyer, S., Boysen, G., & Baldini, G. (2020). Delivery of phosphatidylethanolamine blunts stress in hepatoma cells exposed to elevated palmitate by targeting the endoplasmic reticulum. Cell Death Discov, 6, 8. https://doi.org/10.1038/s41420-020-0241-z

Wongsurawat, T., Jenjaroenpun, P., De Loose, A., Alkam, D., Ussery, D. W., Nookaew, I., Leung, Y. K., Ho, S. M., Day, J. D., & Rodriguez, A. (2020). A novel Cas9-targeted long-read assay for simultaneous detection of IDH1/2 mutations and clinically relevant MGMT methylation in fresh biopsies of diffuse glioma. Acta Neuropathol Commun, 8(1), 87. https://doi.org/10.1186/s40478-020-00963-0

Cellular Physiology and Molecular Biophysics

Cawley, K. M., Bustamante-Gomez, N. C., Guha, A. G., MacLeod, R. S., Xiong, J., Gubrij, I., Liu, Y., Mulkey, R., Palmieri, M., Thostenson, J. D., Goellner, J. J., & O’Brien, C. A. (2020). Local Production of Osteoprotegerin by Osteoblasts Suppresses Bone Resorption. Cell Rep, 32(10), 108052. https://doi.org/10.1016/j.celrep.2020.108052

D’Souza, Z., Taher, F. S., & Lupashin, V. V. (2020). Golgi inCOGnito: From vesicle tethering to human disease. Biochim Biophys Acta Gen Subj, 1864(11), 129694. https://doi.org/10.1016/j.bbagen.2020.129694

Hijazi, H., Coelho, F. S., Gonzaga-Jauregui, C., Bernardini, L., Mar, S. S., Manning, M. A., Hanson-Kahn, A., Naidu, S., Srivastava, S., Lee, J. A., Jones, J. R., Friez, M. J., Alberico, T., Torres, B., Fang, P., Cheung, S. W., Song, X., Davis-Williams, A., Jornlin, C., Wight, P. A., Patyal, P., Taube, J., Poretti, A., Inoue, K., Zhang, F., Pehlivan, D., Carvalho, C. M. B., Hobson, G. M., & Lupski, J. R. (2020). Xq22 deletions and correlation with distinct neurological disease traits in females: Further evidence for a contiguous gene syndrome. Hum Mutat, 41(1), 150-168. https://doi.org/10.1002/humu.23902

Jenkins, S. V., Jung, S., Shah, S., Millett, P. C., Dings, R. P. M., Borrelli, M. J., & Griffin, R. J. (2021). Nanoscale investigation and control of photothermal action of gold nanostructure-coated surfaces. Journal of Materials Science, 56(17), 10249-10263. https://doi.org/10.1007/s10853-021-05947-6

Jung, S., Harris, N., Niyonshuti, II, Jenkins, S. V., Hayar, A. M., Watanabe, F., Jamshidi-Parsian, A., Chen, J., Borrelli, M. J., & Griffin, R. J. (2021). Photothermal Response Induced by Nanocage-Coated Artificial Extracellular Matrix Promotes Neural Stem Cell Differentiation. Nanomaterials (Basel), 11(5). https://doi.org/10.3390/nano11051216

Kim, H. N., Xiong, J., MacLeod, R. S., Iyer, S., Fujiwara, Y., Cawley, K. M., Han, L., He, Y., Thostenson, J. D., Ferreira, E., Jilka, R. L., Zhou, D., Almeida, M., & O’Brien, C. A. (2020). Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence. JCI Insight, 5(19). https://doi.org/10.1172/jci.insight.138815

Patyal, P., Kockara, N. T., & Wight, P. A. (2020). The wmN1 Enhancer Region of the Mouse Myelin Proteolipid Protein Gene (mPlp1) is Indispensable for Expression of an mPlp1-lacZ Transgene in Both the CNS and PNS. Neurochem Res, 45(3), 663-671. https://doi.org/10.1007/s11064-019-02919-w

Sabol, H. M., & Delgado-Calle, J. (2021). The multifunctional role of Notch signaling in multiple myeloma. J Cancer Metastasis Treat, 7. https://doi.org/10.20517/2394-4722.2021.35

Saguyod, S. J. U., Alhallak, I., Simmen, R. C. M., & Velarde, M. C. (2020). Metformin regulation of progesterone receptor isoform-B expression in human endometrial cancer cells is glucose-dependent. Oncol Lett, 20(5), 249. https://doi.org/10.3892/ol.2020.12112

Sumya, F. T., Pokrovskaya, I. D., & Lupashin, V. (2021). Development and Initial Characterization of Cellular Models for COG Complex-Related CDG-II Diseases. Front Genet, 12, 733048. https://doi.org/10.3389/fgene.2021.733048

Microbiology and Immunology

Banerjee, S. K., Crane, S. D., & Pechous, R. D. (2020). A Dual Role for the Plasminogen Activator Protease During the Preinflammatory Phase of Primary Pneumonic Plague. J Infect Dis, 222(3), 407-416. https://doi.org/10.1093/infdis/jiaa094

Crane, S. D., Banerjee, S. K., Eichelberger, K. R., Kurten, R. C., Goldman, W. E., & Pechous, R. D. (2021). The Yersinia pestis GTPase BipA Promotes Pathogenesis of Primary Pneumonic Plague. Infect Immun, 89(2). https://doi.org/10.1128/IAI.00673-20

Graham, D. E., Groshong, A. M., Jackson-Litteken, C. D., Moore, B. P., Caimano, M. J., & Blevins, J. S. (2020). The BB0345 Hypothetical Protein of Borrelia burgdorferi Is Essential for Mammalian Infection. Infect Immun, 88(12). https://doi.org/10.1128/IAI.00472-20

Jackson-Litteken, C. D., Ratliff, C. T., Kneubehl, A. R., Siletti, C., Pack, L., Lan, R., Huynh, T. N., Lopez, J. E., & Blevins, J. S. (2021). The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology. Infect Immun, 89(6). https://doi.org/10.1128/IAI.00787-20

Latham, L. E., Wikenheiser, D. J., & Stumhofer, J. S. (2020). ICOS signaling promotes a secondary humoral response after re-challenge with Plasmodium chabaudi chabaudi AS. PLoS Pathog, 16(4), e1008527. https://doi.org/10.1371/journal.ppat.1008527

Malaviarachchi, P. A., Mercado, M. A. B., McSorley, S. J., & Li, L. X. (2020). Antibody, but not B-cell-dependent antigen presentation, plays an essential role in preventing Chlamydia systemic dissemination in mice. Eur J Immunol, 50(5), 676-684. https://doi.org/10.1002/eji.201948391

Mercado, M. A. B., Du, W., Malaviarachchi, P. A., Gann, J. I., & Li, L. X. (2021). Innate IFN-gamma Is Essential for Systemic Chlamydia muridarum Control in Mice, While CD4 T Cell-Dependent IFN-gamma Production Is Highly Redundant in the Female Reproductive Tract. Infect Immun, 89(3). https://doi.org/10.1128/IAI.00541-20

Phillips, M. B., Dina Zita, M., Howells, M. A., Weinkopff, T., & Boehme, K. W. (2021). Lymphatic Type 1 Interferon Responses Are Critical for Control of Systemic Reovirus Dissemination. J Virol, 95(4). https://doi.org/10.1128/JVI.02167-20

Ramirez, A. M., Beenken, K. E., Byrum, S. D., Tackett, A. J., Shaw, L. N., Gimza, B. D., & Smeltzer, M. S. (2020). SarA plays a predominant role in controlling the production of extracellular proteases in the diverse clinical isolates of Staphylococcus aureus LAC and UAMS-1. Virulence, 11(1), 1738-1762. https://doi.org/10.1080/21505594.2020.1855923

Ramirez, A. M., Byrum, S. D., Beenken, K. E., Washam, C., Edmondson, R. D., Mackintosh, S. G., Spencer, H. J., Tackett, A. J., & Smeltzer, M. S. (2020). Exploiting Correlations between Protein Abundance and the Functional Status of saeRS and sarA To Identify Virulence Factors of Potential Importance in the Pathogenesis of Staphylococcus aureus Osteomyelitis. ACS Infect Dis, 6(2), 237-249. https://doi.org/10.1021/acsinfecdis.9b00291

Neuroscience

Allensworth-James, M., Banik, J., Odle, A., Hardy, L., Lagasse, A., Moreira, A. R. S., Bird, J., Thomas, C. L., Avaritt, N., Kharas, M. G., Lengner, C. J., Byrum, S. D., MacNicol, M. C., Childs, G. V., & MacNicol, A. M. (2021). Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi. Endocrinology, 162(3). https://doi.org/10.1210/endocr/bqaa245

Allensworth-James, M. L., Odle, A. K., Lim, J., LaGasse, A. N., Miles, T. K., Hardy, L. L., Haney, A. C., MacNicol, M. C., MacNicol, A. M., & Childs, G. V. (2020). Metabolic signalling to somatotrophs: Transcriptional and post-transcriptional mediators. J Neuroendocrinol, 32(11), e12883. https://doi.org/10.1111/jne.12883

Izadyar, A., Van, M. N., Rodriguez, K. A., Seok, I., & Hood, E. E. (2021). A bienzymatic amperometric glucose biosensor based on using a novel recombinant Mn peroxidase from corn and glucose oxidase with a Nafion membrane. Journal of Electroanalytical Chemistry, 895, 115387. https://doi.org/https://doi.org/10.1016/j.jelechem.2021.115387

Mehdi, S. H., Nafees, S., Mehdi, S. J., Morris, C. A., Mashouri, L., & Yoon, D. (2021). Animal Models of Multiple Myeloma Bone Disease. Front Genet, 12, 640954. https://doi.org/10.3389/fgene.2021.640954

Miles, T. K., Silva Moreira, A. R., Allensworth-James, M. L., Odle, A. K., Haney, A. C., MacNicol, A. M., MacNicol, M. C., & Childs, G. V. (2020). Sex differences in somatotrope response to fasting: biphasic responses in male mice. J Endocrinol, 247(3), 213-224. https://doi.org/10.1530/JOE-20-0275

Pathobiology

Harrington, W. N., Nolan, J., Nedosekin, D. A., Smeltzer, M. S., & Zharov, V. P. (2020). Real-Time Monitoring of Bacteria Clearance From Blood in a Murine Model. Cytometry A, 97(7), 706-712. https://doi.org/10.1002/cyto.a.23925

Pharmacology, Toxicology, and Experimental Therapeutics

Clemens, M. M., Vazquez, J. H., Kennon-McGill, S., McCullough, S. S., James, L. P., & McGill, M. R. (2020). Pre-treatment twice with liposomal clodronate protects against acetaminophen hepatotoxicity through a pre-conditioning effect. Liver Res, 4(3), 145-152. https://doi.org/10.1016/j.livres.2020.07.002

Cozart, M. A., Phelan, K. D., Wu, H., Mu, S., Birnbaumer, L., Rusch, N. J., & Zheng, F. (2020). Vascular smooth muscle TRPC3 channels facilitate the inverse hemodynamic response during status epilepticus. Sci Rep, 10(1), 812. https://doi.org/10.1038/s41598-020-57733-0

Fulo, H. F., Shoeib, A., Cabanlong, C. V., Williams, A. H., Zhan, C. G., Prather, P. L., & Dudley, G. B. (2021). Synthesis, Molecular Pharmacology, and Structure-Activity Relationships of 3-(Indanoyl)indoles as Selective Cannabinoid Type 2 Receptor Antagonists. J Med Chem, 64(9), 6381-6396. https://doi.org/10.1021/acs.jmedchem.1c00442

Penthala, N. R., Shoeib, A., Dachavaram, S. S., Cabanlong, C. V., Yang, J., Zhan, C. G., Prather, P. L., & Crooks, P. A. (2020). 7-Azaindolequinuclidinones (7-AIQD): A novel class of cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptor ligands. Bioorg Med Chem Lett, 30(22), 127501. https://doi.org/10.1016/j.bmcl.2020.127501

Pinson, A., Yarbrough, A. L., Bush, J. M., Cabanlong, C. V., Shoeib, A., Jackson, B. K., Fukuda, S., Gogoi, J., Fantegrossi, W. E., McCain, K., Prather, P. L., Fujiwara, R., & Radominska-Pandya, A. (2020). Metabolism, CB1 cannabinoid receptor binding and in vivo activity of synthetic cannabinoid 5F-AKB48: Implications for toxicity. Pharmacol Biochem Behav, 195, 172949. https://doi.org/10.1016/j.pbb.2020.172949

Shrum, S., Tobacyk, J., Lo, S., Parajuli, N., & MacMillan-Crow, L. A. (2020). The BK activator NS11021 partially protects rat kidneys from cold storage and transplantation-induced mitochondrial and renal injury. Arch Biochem Biophys, 688, 108410. https://doi.org/10.1016/j.abb.2020.108410

Tobacyk, J., & MacMillan-Crow, L. A. (2021). Fluorescence-Based Assay For Measuring OMA1 Activity. Methods Mol Biol, 2276, 325-332. https://doi.org/10.1007/978-1-0716-1266-8_24

Vazquez, J. H., Clemens, M. M., Allard, F. D., Yee, E. U., Kennon-McGill, S., Mackintosh, S. G., Jaeschke, H., Hambuchen, M. D., & McGill, M. R. (2020). Identification of Serum Biomarkers to Distinguish Hazardous and Benign Aminotransferase Elevations. Toxicol Sci, 173(2), 244-254. https://doi.org/10.1093/toxsci/kfz222

Health Promotion and Prevention Research

Gorvine, M. M., Haynes, T. F., Marshall, S. A., Clark, C. J., Lovelady, N. N., & Zaller, N. D. (2021). An Exploratory Study of the Acceptability and Feasibility of Yoga Among Women in Substance Use Disorder Recovery. J Altern Complement Med, 27(3), 273-281. https://doi.org/10.1089/acm.2020.0351

Gorvine, M. M., Haynes, T. F., Marshall, S. A., Clark, C. J., Lovelady, N. N., & Zaller, N. D. (2021). A Qualitative Exploration of Women’s Lives and Resilience in Substance Use Disorder Recovery. Integr Med (Encinitas), 20(3), 20-29. https://www.ncbi.nlm.nih.gov/pubmed/34377097

Lovelady, N. N., Zaller, N. D., Stewart, M. K., Cheney, A. M., Porter Iii, A., & Haynes, T. F. (2021). Characterizing Firearm Assault Injury Among Young Black Men Using Arkansas Hospital Discharge Data. J Interpers Violence, 886260521997947. https://doi.org/10.1177/0886260521997947

Marshall, S. A., Driver, N., & Allison, M. K. (2021). Attitudes towards contraception: focus groups with Arkansas teenagers and parents. Sex Education, 21(2), 161-175. https://doi.org/10.1080/14681811.2020.1759526

Stewart, M. K., Allison, M. K., Grant Hunthrop, M. S., Marshall, S. A., & Cornell, C. E. (2021). Outcomes Research on Telemedicine-Delivered Gender-Affirming Health Care for Transgender Youth Is Needed Now: A Call to Action. Transgender Health. https://doi.org/10.1089/trgh.2021.0063

Swindle, T., Martinez, A., Borsheim, E., & Andres, A. (2020). Adaptation of an exercise intervention for pregnant women to community-based delivery: a study protocol. BMJ Open, 10(9), e038582. https://doi.org/10.1136/bmjopen-2020-038582

Health Systems and Services Research

Chen, H. F., Landes, R. D., Schuldt, R. F., & Tilford, J. M. (2020). Quality Performance of Rural and Urban Home Health Agencies: Implications for Rural Add-On Payment Policies. J Rural Health, 36(3), 423-432. https://doi.org/10.1111/jrh.12415

Schuldt, R. F., Felix, H. C., & Bradway, C. K. (2021). The impact of severe obesity on home health care agency admission: An organizational perspective. Home Health Care Serv Q, 40(1), 27-38. https://doi.org/10.1080/01621424.2020.1856747

MD/PhD Program

Beenken, K. E., Campbell, M. J., Ramirez, A. M., Alghazali, K., Walker, C. M., Jackson, B., Griffin, C., King, W., Bourdo, S. E., Rifkin, R., Hecht, S., Meeker, D. G., Anderson, D. E., Biris, A. S., & Smeltzer, M. S. (2021). Evaluation of a bone filler scaffold for local antibiotic delivery to prevent Staphylococcus aureus infection in a contaminated bone defect. Sci Rep, 11(1), 10254. https://doi.org/10.1038/s41598-021-89830-z

Gaba, R. C., Elkhadragy, L., Boas, F. E., Chaki, S., Chen, H. H., El-Kebir, M., Garcia, K. D., Giurini, E. F., Guzman, G., LoBianco, F. V., Neto, M. F., Newson, J. L., Qazi, A., Regan, M., Rund, L. A., Schwind, R. M., Stewart, M. C., Thomas, F. M., Whiteley, H. E., Wu, J., Schook, L. B., & Schachtschneider, K. M. (2020). Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation. Oncotarget, 11(28), 2686-2701. https://doi.org/10.18632/oncotarget.27647

LoBianco, F. V., Krager, K. J., Carter, G. S., Alam, S., Yuan, Y., Lavoie, E. G., Dranoff, J. A., & Aykin-Burns, N. (2020). The Role of Sirtuin 3 in Radiation-Induced Long-Term Persistent Liver Injury. Antioxidants (Basel), 9(5). https://doi.org/10.3390/antiox9050409

Tascioglu Aliyev, A., LoBianco, F., Krager, K. J., & Aykin-Burns, N. (2020). Assessment of Cellular Oxidation using a Subcellular Compartment-Specific Redox-Sensitive Green Fluorescent Protein. J Vis Exp(160). https://doi.org/10.3791/61229

Wallis, K. F., Morehead, L. C., Bird, J. T., Byrum, S. D., & Miousse, I. R. (2021). Differences in cell death in methionine versus cysteine depletion. Environ Mol Mutagen, 62(3), 216-226. https://doi.org/10.1002/em.22428

Nursing Science

Hays, L. H., & Beverly, C. (2021). Leadership, health systems and policy: Doctoral education and integrated clinical application. J Prof Nurs, 37(2), 281-285. https://doi.org/10.1016/j.profnurs.2020.12.009

Hays, L., McSweeney, J., Mitchell, A., Bricker, C., Green, A., & Landes, R. D. (2020). Recruitment Issues in Emerging Adult Populations: Focus on Adult Congenital Heart Disease. Nurs Rep, 10(2), 135-145. https://doi.org/10.3390/nursrep10020017

Hays, L. H., McSweeney, J. C., Mitchell, A., Bricker, C., Green, A., & Landes, R. D. (2020). Self-management Needs of Adults With Congenital Heart Disease. J Cardiovasc Nurs, 35(6), E33-E43. https://doi.org/10.1097/JCN.0000000000000701

Pharmaceutical Evaluation and Policy

Hayes, C. J., Krebs, E. E., Hudson, T., Brown, J., Li, C., & Martin, B. C. (2020). Impact of opioid dose escalation on pain intensity: a retrospective cohort study. Pain, 161(5), 979-988. https://doi.org/10.1097/j.pain.0000000000001784

Hayes, C. J., Krebs, E. E., Hudson, T., Brown, J., Li, C., & Martin, B. C. (2020). Impact of opioid dose escalation on the development of substance use disorders, accidents, self-inflicted injuries, opioid overdoses and alcohol and non-opioid drug-related overdoses: a retrospective cohort study. Addiction, 115(6), 1098-1112. https://doi.org/10.1111/add.14940

Nalleballe, K., Sheng, S., Li, C., Mahashabde, R., Annapureddy, A. R., Mudassar, K., Pothineni, K., Veerapaneni, P., Harada, Y., Chilkulwar, A., Ranabothu, S., Brown, A., Kapoor, N., & Onteddu, S. (2020). Industry Payment to Vascular Neurologists: A 6-Year Analysis of the Open Payments Program From 2013 Through 2018. Stroke, 51(4), 1339-1343. https://doi.org/10.1161/STROKEAHA.119.027967

Pharmaceutical Sciences

Pal, S., Sarker, N., Qaria, M., Tandon, K., Akhter, Y., & Ahmed, N. (2020). Design of an inhibitor of Helicobacter pylori cholesteryl-alpha-glucoside transferase critical for bacterial colonization. Helicobacter, 25(5), e12720. https://doi.org/10.1111/hel.12720

Van, S., Pal, S., Garner, B. R., Steed, K., Sridharan, V., Mu, S., Rusch, N. J., & Stolarz, A. J. (2021). Dantrolene Prevents the Lymphostasis Caused by Doxorubicin in the Rat Mesenteric Circulation. Front Pharmacol, 12, 727526. https://doi.org/10.3389/fphar.2021.727526