Dr. Juvvadi’s research is primarily directed toward identifying genes that are indispensable for fungal growth, drug response, and virulence by utilizing various molecular strategies, including genetic, biochemical, and proteomic techniques and animal models of infection. His laboratory research has demonstrated the importance of calcineurin, a calcium-calmodulin-dependent protein phosphatase, for fungal growth and virulence. The overall goal is to elucidate the calcineurin-dependent molecular mechanisms controlling fungal growth, pathogenesis, and drug resistance, utilizing whole proteomic and lipidomic approaches which will ultimately enable the identification of fungal-specific targets to help design potentially more effective strategies to combat IA.