UAMS.EDU

2007-2008 Publications

Student names in bold

Biochemistry and Molecular Biology
Brenner, B., Harney, J., Ahmed, B., Jeffus, B., Unal, R., Mehta, J. and Kilic, F. (2007) Plasma serotonin level and the platelet serotonin transporter. J Neurochem 102:206-216.

Jamakhandi, A., Kuzmic, P., Sanders, D. and Miller, G. (2007) Global analysis of protein-protein interactions reveals multiple CYP2E1-reductase complexes. Biochemistry 46:10192-201.

Jennings, T.A., Chen, Y., Sikora, D., Harrison, M.K., Sikora, B., Huang, L., Jankowsky, E., Fairman, M.E., Cameron, C.E. and Raney, K.D. (2008) RNA unwinding activity of the hepatitis C virus NS3 helicase Is modulated by the NS5B polymerase. Biochemistry 47:1126-1135.

Kolomeichuk, S., Bene, A., Upreti, M., Dennis, R., Lyle, C., Rajasekaran, M. and Chambers, T. (2008) Induction of apoptosis by vinblastine via c-Jun autoamplification and p53-independent down-regulation of p21 WAF1/CIP1. Mol Pharmcol 73:128-36.

Kolomeichuk, S., Terrano, D., Lyle, C., Sabapathy, K. and Chambers, T. (2008) Distinct signaling pathways of microtubule inhibitiors-vinblastine and taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively. FEBS J, Mar 13:[Epub ahead of print].

Sikora, B., Chen, Y., Lichti, C.F., Harrison, M.K., Jennings, T.A., Tang, Y., Tackett, A.J., Jordan, J.B., Sakon, J., Cameron, C.E. and Raney, K.D. (2008) Hepatitis C Virus NS3 helicase forms oligomeric structures that exhibit optimal DNA unwinding activity in vitro. J Biol Chem, Feb 18:[Epub ahead of print].

Starlard-Davenport, A., Lyn-Cook, B. and Radominska-Pandya, A. (2008) Novel identification of UDP-glucuronosyltransferase 1A1- as an estrogen-regulated target gene. Steroids 73:139-147.

Xiong, Y., Patana, A., Miley, M., Zielinska, A., Bratton, S., Miller, G., Goldman, A., Finel, M., Redinbo, M. and Radominska-Pandya, A. (2008) The First Aspartic Acid of the DQxD Motif for Human UDP-Glucuronosyltransferase 1A10 Interacts with UDP-Glucuronic Acid During Catalysis. Drug Metab Dispos 36: 517-22.

Bioinformatics
Bhattacharyya, S., Byrum, S., Siegel, E.R. and Suva, L.J. (2007) Proteomic analysis of bone cancer: a review of current and future developments. Expert Rev Proteomics 4:371-378.

Bhattacharyya, S., Siegel, E., Achenbach, S., Khosla, S. and Suva, L. (2008) A Serum Biomarker Profile Associated with High Bone Turnover and Bone Mineral Density in Postmenopausal Women. J Bone Miner Res, Feb 26:[Epub ahead of print].

Communication Disorders
Kolomeichuk, S., Bene, A., Upreti, M., Dennis, R., Lyle, C., Rajasekaran, M. and Chambers, T. (2008) Induction of apoptosis by vinblastine via c-Jun autoamplification and p53-independent down-regulation of p21 WAF1/CIP1. Mol Pharmcol 73:128-36.

Kolomeichuk, S., Terrano, D., Lyle, C., Sabapathy, K. and Chambers, T. (2008) Distinct signaling pathways of microtubule inhibitiors-vinblastine and taxol induce JNK-dependent cell death but through AP-1-dependent and AP-1-independent mechanisms, respectively. FEBS J, Mar 13:[Epub ahead of print].

Morgan, J., Zraick, R., Griffin, A., Bowen, T. and Johnson, F. (2007) Injection vs. medialization laryngoplasty for the treatment of unilateral vocal fold paralysis. Laryngoscope 117:1-7.

Health Systems Research
Cleves, M., Hobbs, C., Cleves, P., Tilford, J., Bird, T. and Robbins, J. (2007) Congenital defects among liveborn infants with Down syndrome. Birth Defects Res A Clin Mol Teratol 79:657-63.

Interdisciplinary Biomedical Sciences
Boctor, S., 
Jr., J.M., Koek, W. and France, C. (2007) The cannabinoid CB(1) receptor antagonist AM251 does not modify methamphetamine reinstatement of responding. Eur J Pharmacol 571:39-43.

El-Jouni, W., Haun, S., Hodeify, R., Walker, A.H. and Machaca, K. (2007) Vesicular traffic at the cell membrane regulates oocyte meiotic arrest. Development 134:3307-3315. 

Jain, S., Zuka, M., Liu, J., Russell, S., Dent, J., Guerrero, J., Forsyth, J., Maruszak, B., Gartner, T., Feldin-Haberman, B. and Ware, J. (2007) Platelet glycoprotein lbα supports experimental lung metastasis. Proc Natl Acad Sci USA 104:9024-9028.

Miley, M., Zielinska, A., Keenan, J., Bratton, S., Radominska-Pandya, A. and Redinbo, M. (2007) Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7. J Mol Biol 369:498-511.

Rodriguez, J., Boctor, S., Phelix, C. and Martinez Jr., J.L. (2008) Differences in performance between Sprague-Dawley and Fischer 344 rats in positive reinforcement tasks. Pharmacol Biochem Behav 89:17-22.

Rose, S., Melnyk, S., Savenka, A., Hubanks, A., Jernigan, S., Cleves, M. and James, S.J. (2008) The Frequency of polymorphisms affecting lead and mercury toxicity among children with autism. Am J Biochem Biotech 4:85-94.

Sun, L., Hodeify, R., Haun, S., Charlesworth, A., Macnicol, A., Ponnappan, S., Ponnappan, U., Prigent, C. and Machaca, K. (2007) Ca2+ homeostasis regulates Xenopus oocyte maturation. Biol Reprod 78:726-735.

Xiong, Y., Patana, A., Miley, M., Zielinska, A., Bratton, S., Miller, G., Goldman, A., Finel, M., Redinbo, M. and Radominska-Pandya, A. (2008) The First aspartic acid of the DQxD motif for human UDP-Glucuronosyl-transferase 1A10 interacts with UDP-Glucuronic Acid during catalysis. Drug Metab Dispos 36:517-22.

Zhang, X., Azhar, G., Helms, S., Zhong, Y. and Wei, J.Y. (2008) Identification of a subunit of NADH- dehydrogenase as a p49/STRAP-binding protein. BMC Cell Biol, Jan 29:[Epub ahead of print].

Zielinska, A., Lichti, C., Bratton, S., Mitchell, N., Gallus-Zawada, A., Le, V., Finel, M., Miller, G., Radominska-Pandya, A. and Moran, J. (2008) Glucuronidation of mohondroxylated warfarin metabolites by human liver microsomes and human recombinant UDP-Glucuronosyltransferases. J Pharmacol Exp Ther 324:139-148.

Interdisciplinary Toxicology
Bryan, R.M., Joseph, B.K., Lloyd, E. and Rusch, N.J. (2007) Starring TREK-1: The Next generation of vascular K+ channels. Circ Res 101:119-121.

Burke, A.S., Redeker, K., Kurten, R.C., James, L.P. and Hinson, J.A. (2007) Mechanisms of chloroform- induced hepatotoxicity: Oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes. J Toxicol Environ Health A 70:1936-1945

Fraley, K. and McMillan, D. (2008) Effects of gamma-hydroxybutyrate on punished responding in pigeons. Behav Pharmacol 19:77-79.

Joseph, B.K., Rhee, S.W., Hirenallur, D.K. and Rusch, N.J. (2007) Potassium channel vascular smooth muscle: Structure, function and experimental interventions. New Frontier. Smooth Muscle Biology and Physiology. Research Signpost, pp. 173-194.

Shankar, K., Liu, X., Singhal, R., Chen, J., Nagarajan, S., Badger, T. and Ronis, M. (2007) Chronic ethanol consumption leads to disruption of vitamin D3 homeostasis associated with induction of renal 1/ 25 Dihdryoxyvitamin D3 24-hydroxylase (CYP24A1). Endocrinology 149:1748-1756. Singhal, R., Badger, T. and Ronis, M. (2008) Rats fed soy protein isolate (SPI) have impaired hepatic CYP1A1 induction by polycyclic aromatic hydocarbons as a result of interference with aryl hydrocarbon receptor signaling. Toxicol Appl Pharmacol 227:275-83.

Singhal, R., Shankar, K., Badger, T. and Ronis, M. (2008) Estrogenic status modulates aryl hydrocarbon receptor–mediated hepatic gene expression and carcinogenicity. Carcinogenesis 29:227-36.

Microbiology and Immunology
Ward, T., Traina-Dorge, V., Davis, K. and Gray, W. (2008) Recombinant simian varicella virus vaccines expressing the respiratory syncytial virus antigens are immunogenic. J Gen Virol 89:731-740.

Neurobiology and Developmental Sciences
Crane, C., Akhter, N., Johnson, B., Iruthayanthan, M., Syed, F., Kudo, A., Zhou, Y. and Childs, G. (2007) Fasting and glucose effects on pituitary leptin expression: is leptin a local signal for nutrient status? J Histochem Cythochem 55:1059-73.

Garcia-Rill, E., Heister, D., Ye, M., Charlesworth, A. and Hayar, A. (2007) Electrical coupling: novel mechanism for sleep-wake control. Sleep 30:1405-14.

Kielian, T., Esen, N., Liu, S., Phulwani, N., Nishina, K., Cheung, A., Schwartzman, J. and Ruhe, J. (2007) Minocycline modulates neuroinflammation independently of its anti-microbial activity in S. aureus induced brain abscess. Am J Pathol 171:1199-1214.

Kielian, T., Phulwani, N., Esen, N., Syed, M., Haney, A., McCastlain, K. and Johnson, J. (2007) MyD88-dependent signals are essential for the host immune response in experimental brain abscess. J Immunol 178: 4528-4537.

Syed, M., Phulwani, N. and Kielian, T. (2007) TNF-α regulates Toll-like receptor 2 (TLR2) expression in microglia. J Neurochem 103:1461-1471.

Nursing Science
Abbott, R. (2008) Geographical analysis of ambulance availability in Arkansas. Fam Community Health 31:35-43.

Pate, B. (2008) Identifying and tracking disaster victims-State-of-the-art technology review. Fam Community Health 31:23-24.

Richards, K., Enderlin, C., Beck, C., McSweeney, J., Jones, T. and Roberson, P. (2007) Tailored biobehavioral interventions: A literature review and synthesis. Res Theory Nurs Pract 21:271-285.

Richards, K., Roberson, P., Simpson, K., Lambert, C., Bliwise, D., Cole, C., Enderlin, C.and Shue, V. (2008) Periodic leg movements predict total sleep time in persons with cognitive impairment and sleep disturbance. Sleep 3:224-230.

Pharmacology
Baumgardner, J.N., Hennings, L., Shankar, K., Badger, T.M. and Ronis, M.J.J. (2008) A New animal model for non-alcoholic steatohepatitis utilizing total enteral nutrition (TEN) to overfeed the rat a diet high in polyunsaturated fat. Am J Physiol Gastrointest Liver Physiol 294:G27-38.

Baumgardner, J.N., Shankar, K., Korourian, S., Badger, T.M. and Ronis, M.J. (2007) Undernutrition enhances alcohol-induced hepatocyte proliferation in the liver of rats fed via total enteral nutrition. American Journal Physiol Gastrointest Liver Physiol 293:355-364.

Saba, H., Munusamy, S. and Macmillan-Crow, L. (2008) Cold preservation mediated renal injury: involvement of mitochondrial oxidative stress. Ren Fail 30:125-33.

Telemaque, S., Sonkusare, S., Grain, T., Rhee, S., Stimers, J., Rusch, N. and Marsh, J. (2008) Design of mutant {beta} 2 subunits as decoy molecules to reduce the expression of functional Ca2+ channels in cardiac cells. J Pharmacol Exp Ther 325:37-46.

Shaik, Z.P., Fifter, E.K. and Nowak, G. (2008) Akt activation improves oxidative phosphorylation in renal proximal tubular cells following nephrotoxicant injury. Am J Physiol Renal Physiol 294:F423-432.

Physiology and Biophysics
Ball, K., Gandhi, G., Thrash, J., Cruz, N. and Dienel, G. (2007) Astrocytic connexin distributions and rapid, extensive dye transfer via gap junctions in the inferior colliculus: Implications for [(14)C]glucose metabolite trafficking. J Neurosci Res 85:3267-83.

Chowdhury, P., Soulsby, M. and Kim, K. (2007) L-carnitine influence on oxidative stress induced by hind-limb unloading in adults rats. Aviat Space Environ Med 78:554-556.

El-Jouni, W., Haun, S., Hodeify, R., Walker, A.H. and Machaca, K. (2007) Vesicular traffic at the cell membrane regulates oocyte meiotic arrest. Development 134:3307-3315.

Jennings, M., Howren, T., Cui, J., Winters, M. and Hannigan, R. (2007) Transport and regulatory characteristics of the yeast bicarbonate transporter homolog Bor1p. Am J Physiol Cell Physiol 293:C468-C476.

Johnson, S., Ramani, V., Hennings, L. and Haun, R. (2007) Kallikrein 7 enhances pancreatic cancer cell invasion by shedding E-cadherin. Cancer 109:1811-1820.

Kadri, P., Krisht, A. and Gandhi, G. (2007) An anatomic mathematical measurement to find an adequate recipient M4 branch for superficial temporal artery to middle cerebral artery bypass surgery. Neurosurgery 61:74-8.

Ramani, V. and Haun, R. (2008) The extracellular matrix protein fibronectin is a substrate for kallikrein 7. Biochem Biophys Res Commun, Mar 13:[Epub ahead of print].

Sehgal, S. and Storrie, B. (2007) Evidence that differential packaging of the major platelet granule proteins von Willebrand factor and fibrinogen can support their differential release. J Thromb Haemost 5:2009-16.

Shestakova, A., Suvorova, E., Pavliv, O., Khaidakova, G. and Lupashin, V. (2007) Interaction of the conserved oligomeric golgi complex with t-SNARE syntaxin5a/Sed5 enhances intra-golgi SNARE complex stability. J Cell Biol 179:1179-1192.

Smith, R. and Lupashin, V. (2008) Mini-Review: Role of the conserved oligomeric golgi (COG) complex in protein glycosylation. Carbohydr Res, Feb 2:[Epub ahead of print].

Sun, L., Chai, Y., Hannigan, R., Bhogaraju, V.K. and Machaca, K. (2007) Zinc regulates the ability of Cdc25C to activate MPF/cdk 1. J Cell Physiol 213:98-104.

Sun, Y., Shestakova, A., Hunt, L., Sehgal, S., Lupashin, V. and Storrie, B. (2007) Rab6 regulates both ZW10/RINT-1 and conserved oligomeric golgi complex-dependent golgi trafficking and homeostasis. Mol Biol Cell 18:4129-42.

Velarde, M.C., Zeng, Z., McQuown, J.R., Simmen, F.A. and Simmen, R.C.M. (2007) Kruppel-Llike Factor 9 is a negative regulator of ligand-dependent estrogen receptor a signaling in Ishikawa endometrial adenocarcinoma cells. Mol Endocrinol 21:2988-3001.

Xiao, R., Hennings, L., Badger, T. and Simmen, F. (2007) Fetal programming of colon cancer in adult rats: correlations with altered neonatal growth trajectory, circulating IGF-1 and IGS binding proteins, and testosterone. J Endocrinol 195:79-87.

Xiao, R., Su, Y., Simmen, R. and Simmen, F. (2008) Dietary soy protein inhibits DNA damage and cell survival of colon epithelial cells through attenuated expression of fatty acid synthase. Am J Physiol Gastrointest Liver Physiol, Jan 31:[Epub ahead of print].

Zeng, Z., Velarde, M., Simmen, F. and Simmen, R. (2008) Delayed parturition and altered myometrial progesterone receptor isoform A expression in mice null for Kruppel-like Factor 9. Biol Reprod, Feb 27:[Epub ahead of print].