Cellular and Molecular Immunology and Immunopathology Track
Track Leader-Usha Ponnappan, Ph.D.
Nalini Bora, Ph.D. (Ophthalmology, Jones Eye Institute) Web profile
My research is focused upon the understanding of biochemical, immunological and molecular mechanisms of various ocular diseases such as uveitis, age-related macular degeneration (AMD), keratitis and ocular tumors.
Marie Chow, Ph.D. (Microbiology and Immunology) Web profile
The research program uses RNA viruses to study host physiological processes (such as RNA interference), the cell biology of the virus replication cycle (such as virus entry and exit) and the role of virus-induced immune responses in neurodegenerative diseases (such as post-polio syndrome).
Kathleen Gilbert, Ph.D. (Microbiology and Immunology) Web profile
We study the role of environmental toxicants in initiating autoimmune disease, and use histone deacetylase inhibitors to block T cell activity and reverse autoimmune disease.
Mayumi Nakagawa, M.D., Ph.D. (Pathology)
T cell immunity to human papillomavirus as it relates to the development of therapeutic vaccines and immunotherapy.
S. Michael Owens, Ph.D. (Pharmacology and Toxicology) Web profile
The research program is aimed at discovering monoclonal antibody-based medications for the treatment of medical problems caused by drug abuse.
Usha Ponnappan, Ph.D. (Microbiology and Immunology) Web profile
Our research is focused on understanding the role of ubiquitin proteasome pathway in transcriptional regulation, immune signaling and in the induction and regulation of transcription factor NF kappa B in innate and adaptive immunity. Additionally, our efforts are directed at dissecting the role of redox regulation in immune senescence and inflammation.
Steve Post, Ph.D. (Pathology) Web profile
Our lab studies the coupling of specific receptors and signaling pathways to cell function and disease. Of particular interest are the regulation of macrophage scavenger receptors and their role in chronic inflammation. Another area of interest relates to understanding the signaling pathways that regulate cardiac myocyte survival.
Roger G. Rank, Ph.D. (Microbiology and Immunology) Web profile
My research entails the study of immunity and immunopathogenesis in genital and ocular infections caused by Chlamydia.
Lee S.F. Soderberg, Ph.D. (Microbiology and Immunology) Web profile
Certain toxic compounds suppress immunity by modulating signal transduction and proteasome function and result in increased tumor growth.
Xuming Zhang, Ph.D. (Microbiology and Immunology) Web profile
To elucidate the mechanisms and regulation of coronavirus RNA synthesis, the molecular pathogenesis of coronavirus-induced neurodegenerative diseases, and virus-host cell interactions.